STEPHEN LAWRENCE CRAIG
Assistant Professor, Department of Chemistry

Contact Information
310 P.M. Gross Chemical Laboratory
(PH) 919-660-1538
(FX) 919-660-1605
stephen.craig@duke.edu

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Education

	PhD	Dynamics and Mechanisms of Gas Phase Ion–Molecule Reactions, Chemistry, Stanford University, 1997
	M.Phil	Organic Reactivity Studied by Intermolecular Perturbation Theory, Theoretical Chemistry, Cambridge University, 1992
	BS	Chemistry, Duke University, 1991

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Experience

	2000-present	Assistant Professor, Department of Chemistry, Duke University
	1999-2000	NIH Postdoctoral Fellow, Scripps Research Inst., Chemistry
	1997-1999	1997-1999 Research Chemist, Central Research Department, DuPont

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Selected Publications

Most closely related to this proposal

1. E. A. Fogleman, W. C. Yount, J. Xu, and S. L. Craig, "Modular, Well–Behaved Reversible Polymers from DNA–Based Monomers", Angew. Chem. Int. Ed., 2002, 41, 4026-4028.
2. R. K. Castellano, R. Clark, S. L. Craig, C. Nuckolls, and J. Rebek, Jr. “Self-Assembled Polymers Exhibit Emergent Mechanical Properties in Solution and the Solid State,” Proc. Natl. Acad. Sci. USA, 2000, 97, 12418-12421.
3. S. Körner, J. Chen, S. L. Craig, D. Rudkevich, and J. Rebek, Jr., “Chemical Amplification Through Compartmentalized Reagents”, Nature, 2002, 415, 385-386.
4. F. Hof, S. L. Craig, C. Nuckolls, J. Rebek, Jr., "Molecular Encapsulation", Angew. Chem. Int. Ed., 2002, 41, 1488–1508.
5. R. K. Castellano, S. L. Craig, C. Nuckolls, and J. Rebek, Jr. “Detection and Mechanistic Studies of Multi-Component Assembly by Fluorescence Resonance Energy Transfer,” J. Am. Chem. Soc., 2000, 122, 7876-7882.
   

Unrelated to this proposal

1. S. L. Craig and J. I. Brauman. "Perturbed Equilibria and Statistical Energy Redistribution in a Gas Phase SN2 Reaction,” Science, 1997, 276, 1536-8.
2. M. L. Chabinyc, S. L. Craig, C. K. Regan and J. I. Brauman. “Gas-Phase Ionic Reactions: Dynamics and Mechanism of Nucleophilic Displacements,” Science, 1998, 279, 1882-6.
3. S. L. Craig, M. Zhong and J. I. Brauman. "Nonstatistical Reactivity in a Vibrationally Excited SN2 Intermediate,” J. Am. Chem. Soc., 1998, 120, 12125–6.
4. R. K. Castellano, S. L. Craig, C. Nuckolls, and J. Rebek, Jr. “Detection and Mechanistic Studies of Multi-Component Assembly by Fluorescence Resonance Energy Transfer,” J. Am. Chem. Soc., 2000, 122, 7876-7882.
5. C. K. Regan, S. L. Craig, and J. I. Brauman, "Solvent Dependence on Steric Effects in SN2 Reactions", Science, 2002, 295, 2245–2247.
   

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Synergistic Activities

Consultant, E.I. DuPont de Nemours and Co., Central Research Department (1999-2001)

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Collaborators & Other Affiliations

Collaborators:

• Dr. Ross Clark, Kelco Biopolymers, San Diego, CA
• Prof. Colin Nuckolls, Columbia University
• Dr. Yves Termonia, E.I. DuPont de Nemours and Co., Central Research Department
• "Development and Construction of Single Molecule Force Spectrometers for Research and Student Training", with Stefan Zauscher, Rob Clark, David Needham and Harold Erickson, Duke University

Graduate and Post Doctoral Advisors:

• Prof. John I. Brauman, Stanford University
• Dr. Ed Wasserman, American Chemical Society and E. I. DuPont de Nemours & Co.
• Prof. Julius Rebek, Jr., The Skaggs Institute for Chemical Biology, Scripps Research Institute
  

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Short Research Interest Description

Synthetic chemistry directed toward self-assembling materials systems

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Research Interest

Our research interests bridge synthetic organic, physical, and materials chemistry. A primary theme is that of the rational, molecular design of materials formed by self-assembly -- small molecules that spontaneously organize into larger, complex structures with new properties. We are working to understand the relationship between the properties of the molecular components and those of the material, and then to use that knowledge to direct our synthetic efforts. Current interests include (a) the design and synthesis of self-healing polymers, (b) crystal engineering directed by hydrogen bonding, and (c) reversible, selective noncovalent modification of single-walled carbon nanotubes

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